Masaharu Isobe

USPTO Granted Patents = 7 (Patent Applications = 1)

EPO Patents = 6 (Patent Applications = 8)

Average Co-Inventor Count = 2.1

ph-index = 1

Forward Citations = 1(Granted Patents)

Company Filing History:

7 out of 38

The University of Toyama

where one patent can have more than one assignee

Years Active: 2014-2024

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7 patents (USPTO):Sort by Forward CitationsExplore Patents

1. 11970549 - Antibody capable of binding specifically to 5′ to 3′ exonuclease active domain of DNA polymerase (2024-04-30),

2. 10416165 - Method for producing antigen specific monoclonal antibody (2019-09-17),

3. 9625464 - Fluorescent probe for plasma cell identification and isolation, and plasma cell identification or isolation method using the probe (2017-04-18),

4. 9487583 - Method for selecting plasma cells or plasmablasts, method for producing target antigen specific antibodies, and novel monoclonal antibodies (2016-11-08),

5. 8999673 - Method for specifically producing a joined DNA fragment comprising a sequence derived from a target gene (2015-04-07),

6. 8993241 - Reaction device, reaction method and method of synthesizing cDNA (2015-03-31),

7. 8841094 - Homologous recombination method, cloning method, and kit (2014-09-23),

Title: The Innovative Path of Masaharu Isobe

Introduction

Masaharu Isobe, an accomplished inventor based in Toyama, Japan, holds an impressive portfolio of seven patents. His contributions to the field of biotechnology, particularly in the development of monoclonal antibodies, underscore his innovative spirit and dedication to scientific advancement.

Latest Patents

Isobe's latest inventions include an antibody capable of binding specifically to the 5′ to 3′ exonuclease active domain of DNA polymerase. This invention provides a unique antibody that notably inhibits the exonuclease activity of DNA polymerase, facilitating advancements in genetic research and application. Another significant patent he has contributed to is a method for producing antigen-specific monoclonal antibodies. This intricate method aids in separating cells capable of producing target antigen-specific monoclonal antibodies (TASMAs), using a novel approach with a reversible crosslinking agent. Additionally, his research has led to the disclosure of monoclonal antibodies specific to phosphorylated proteins, such as threonine 18 phosphorylated p53 and threonine 68 phosphorylated CHK2.

Career Highlights

Throughout his career, Isobe has been affiliated with prominent institutions that have fostered his research capabilities. He has worked at the University of Toyama and Toyobo Co., Ltd., where he was instrumental in various projects that pushed the boundaries of biotechnological innovation. His commitment to research and development has placed him at the forefront of advancements in the field.

Collaborations

Isobe has collaborated with several notable colleagues, including Nobuyuki Kurosawa and Takafumi Yoshikane. These partnerships have not only enhanced his research endeavors but have also contributed to significant breakthroughs in their respective fields. Collaborating with such talented individuals has undoubtedly amplified the impact and applicability of his inventions.

Conclusion

Masaharu Isobe's innovative contributions through his patents exemplify the spirit of invention that drives progress in biotechnology. His latest patents, career accomplishments, and collaborative efforts highlight the importance of research and development in addressing challenges within scientific environments. As he continues to build on his legacy of innovation, Isobe remains a pivotal figure in the realm of biotechnology.

This text is generated by artificial intelligence and may not be accurate.