Company Filing History:
Years Active: 1994-2001
Title: Mary P. Zimmerman: Innovator in Cysteine Protease Inhibitors
Introduction
Mary P. Zimmerman, based in Pleasanton, California, is a prominent inventor with a notable portfolio of seven patents. Her innovative work primarily focuses on cysteine protease inhibitors, contributing significantly to advancements in biochemistry and pharmacology.
Latest Patents
Zimmerman's latest patents present a class of cysteine protease inhibitors designed to inactivate specific cysteine proteases by covalently bonding to them and releasing heterocyclic leaving groups. One of her innovative claims details the construction of these inhibitors, comprising a first portion that targets the desired cysteine protease while positioning the inhibitor near the thiolate anion of the protease's active site. The second portion forms a covalent bond with the cysteine protease, providing a carbonyl that is attacked by the thiolate to irreversibly deactivate the target protease. Furthermore, her research also explores α-(1,3- or 1,2-dicarbonylenol ether methyl ketones) as a means to deactivate cysteine proteases through similar covalent bonding mechanisms.
Career Highlights
Mary P. Zimmerman is currently associated with Prototek, Inc., where she has made significant advancements in enzyme inhibitors. Her approach to developing cysteine protease inhibitors has paved the way for new therapeutic applications, making her a key figure in her field. Her innovative ideas have not only resulted in multiple patents but have also established her reputation as an influential inventor.
Collaborations
Throughout her career, Zimmerman has collaborated with esteemed colleagues, such as Robert E. Smith and Mark Becker. These collaborations have likely played a pivotal role in refining her inventions and enhancing the impact of her work in the scientific community.
Conclusion
Mary P. Zimmerman exemplifies innovation in the realm of biochemistry and pharmacology, with her work on cysteine protease inhibitors standing out as a significant contribution. Her patents not only highlight her expertise as an inventor but also reflect her commitment to developing solutions that can potentially lead to important therapeutic advancements.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.