Company Filing History:
2 out of 25 
2 out of 548 
Years Active: 2021-2025
Title: Mary Markiewicz: Innovator in Cell Therapy
Introduction
Mary Markiewicz, located in Leawood, Kansas, is an accomplished inventor with a focus on cutting-edge innovations in cell therapy. With a remarkable portfolio of two patents, her work is geared towards advancing treatments for inflammatory disorders and immune system-related conditions.
Latest Patents
Mary's latest patents revolve around engineered regulatory T cells, specifically cell therapy compositions that involve engineered human regulatory T cells (eTregs). These are characterized by ectopic overexpression of FOXP3 and Helios protein. The patents detail methods for producing FOXP3+Helios+ eTregs through the introduction of separate nucleic acid constructs encoding FOXP3 and Helios. Additionally, her patents describe cell therapy compositions that include mixed populations of CD4+ and CD8+ Treg cells, each with ectopic overexpression of these regulatory proteins. The innovations aim to offer novel therapeutic approaches for conditions involving inflammation and disorders of the immune system.
Career Highlights
Mary has significantly contributed to her field through her roles at reputable institutions such as Children's Mercy Hospital and the University of Kansas. Her work in these environments has allowed her to develop her groundbreaking research into practical applications, showcasing her expertise in biomedical innovation.
Collaborations
Throughout her career, Mary has collaborated with notable professionals, including her coworkers Amara Seng and Ryan Fischer. These partnerships have played a crucial role in refining her research and advancing the understanding of engineered regulatory T cells.
Conclusion
Mary Markiewicz is a notable inventor whose contributions to the field of cell therapy hold the promise of improving treatments for immune system disorders. With her innovative patents and collaborations, she exemplifies the dynamic role that inventors play in advancing medical science. Her ongoing work is sure to have lasting impacts in health care and research.