Location History:
- Cambridge, MA (US) (2010)
- New York, NY (US) (2014)
Company Filing History:
Years Active: 2010-2014
Title: Celebrating the Innovations of Mary M. Rozenman
Introduction
Mary M. Rozenman is an accomplished inventor based in New York, NY, whose contributions to the field of chemistry include the development of innovative reaction discovery systems and methodologies. With a total of two patents, her work has significantly advanced the capabilities in organic chemistry and biochemistry.
Latest Patents
Mary Rozenman's most recent inventions include a novel reaction discovery system and a palladium-catalyzed carbon-carbon bond forming reaction. The reaction discovery system is particularly groundbreaking as it allows exploration of reaction conditions that do not depend on DNA duplex formation. This system enhances the flexibility of reactions, enabling the use of organic solvents, higher temperatures, and water-insoluble reagents, catalysts, and ligands. Moreover, it incorporates single-stranded oligonucleotide templates with covalently attached substrate pairs, facilitating new methods for screening reaction conditions.
The palladium-catalyzed carbon-carbon bond forming reaction showcases the application of DNA-templated chemistry to establish enones through the coupling of terminal alkynes and alkenes. This innovative reaction can proceed with a catalytic amount of palladium in the presence of an oxidant and is compatible with various organic solvents and aqueous solutions. This method has proven particularly useful in synthesizing macrocycles, further establishing Rozenman's impact on synthetic organic chemistry.
Career Highlights
Mary currently works at Harvard College, where she harnesses her expertise in chemistry to mentor the next generation of scientists while pursuing her innovative research endeavors. Her pioneering work has paved the way for advancements in chemical synthesis and reaction methodologies.
Collaborations
Throughout her career, Mary Rozenman has collaborated with notable scientists, including David R. Liu and Matthew William Kanan. Such partnerships highlight her ability to work effectively within interdisciplinary teams to drive forward innovative research and applications in chemistry.
Conclusion
Mary M. Rozenman's significant contributions to the field of chemistry through her innovative patents position her as a notable figure in the realm of scientific invention. Her work continues to inspire new research directions and methodologies, underscoring the importance of creativity and collaboration in scientific discovery.