Company Filing History:
Years Active: 1981-1982
Title: Mary M Hitt: Innovator in Cell Culture Technology
Introduction
Mary M Hitt is a prominent inventor based in St. Louis, MO (US), known for her significant contributions to the field of cell culture technology. With a total of 3 patents to her name, she has developed innovative methods that enhance the growth and maintenance of anchorage-dependent cells.
Latest Patents
One of her latest patents is titled "Method of growing anchorage-dependent cells." This invention describes a process where anchorage-dependent cells are cultivated in an agitated microcarrier suspension. The method involves periodically providing a temporary residence for the microcarriers and cells outside the main agitation zone, allowing them to aggregate and undergo gentle tumbling within a confined space that maintains similar environmental conditions to the main reactor.
Another notable patent is the "Cell culture method and apparatus." This invention presents a cell culture system designed for the agitated suspension culturing of mammalian cells. The apparatus features a flask assembly where the culture medium and cells are gently agitated by a slowly rotating agitator. The agitator includes at least one flexible sheet with a large surface area, which billows like a sail as liquid spills from its trailing edge during rotation.
Career Highlights
Mary M Hitt has made significant strides in her career, particularly through her work at Monsanto Company. Her innovative approaches to cell culture have not only advanced scientific understanding but also contributed to practical applications in biotechnology and pharmaceuticals.
Collaborations
Throughout her career, Mary has collaborated with notable colleagues, including William R Tolbert and Joseph Feder. These partnerships have fostered a collaborative environment that encourages the exchange of ideas and advancements in their respective fields.
Conclusion
Mary M Hitt's contributions to cell culture technology exemplify her dedication to innovation and scientific progress. Her patents reflect a commitment to improving methods for growing anchorage-dependent cells, which have important implications in various biotechnological applications.