Company Filing History:
Years Active: 1993-2001
Title: Mary Ellen Snider: Innovator in Monoclonal Antibodies
Introduction
Mary Ellen Snider is a distinguished inventor based in Ledyard, Connecticut, known for her significant contributions to the field of immunology. With a total of five patents to her name, she has made remarkable advancements in the development of monoclonal antibodies that target specific regions of the T cell antigen receptor.
Latest Patents
Her latest patents include innovative monoclonal antibodies that recognize defined regions of the T-cell receptor (TCR). One of her notable inventions provides monoclonal antibodies that are reactive with a constant region of the alpha chain of the TCR. Specifically, she has developed two monoclonal antibodies, termed αF1 and αF2, which react with different epitopes on the framework region of the α monomer of the TCR molecule. Additionally, her work includes monoclonal antibodies that target variable regions of the beta chain of the TCR, specifically W112 and 2D1, which react with β chain variable regions Vβ5.3 and Vβ8.1, respectively. Furthermore, she has developed monoclonal antibody δTCS1, isotype IgG2a, which is reactive with a variable region of the delta chain of the TCR. These monoclonal antibodies hold significant value in both diagnosis and therapy, serving as essential tools for the study of the immune system.
Career Highlights
Throughout her career, Mary Ellen Snider has worked with prominent companies such as Astra Ab and T Cell Sciences, Inc. Her expertise in the field has allowed her to make substantial contributions to the understanding and application of monoclonal antibodies in medical science.
Collaborations
Mary Ellen has collaborated with notable colleagues, including Robert V. Skibbens and Larry D. Henry, further enhancing her research and development efforts in immunology.
Conclusion
Mary Ellen Snider's innovative work in the field of monoclonal antibodies has made a lasting impact on immunology and therapeutic applications. Her contributions continue to advance the understanding of the immune system and its complexities.
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