This inventor holds 1 USPTO granted patent. Top assignee: The United States of America, as Represented by the Secretary, Department of Health and Human Services. Active years: 2003.
Company Filing History:
Years Active: 2003
Title: The Innovative Contributions of Mary Carrington
Introduction
Mary Carrington is a notable inventor based in Gaithersburg, MD (US). She has made significant contributions to the field of medical research, particularly in relation to HIV infection. Her work has implications for understanding the genetic factors that influence the progression of AIDS.
Latest Patents
Mary Carrington holds a patent for her invention titled "Delayed progression to AIDS by a missense allele of the CCR2 gene." This invention relates to a CCR2 deletion mutant, designated “CCR2-64I.” The CCR2 gene is a C—C chemokine receptor that has been implicated as a co-receptor for HIV-1. It has been discovered that the presence of the CCR2-64I allele correlates with a postponement of AIDS outcomes. Infected individuals who possess the CCR2-64I allele are at a reduced risk for progression from HIV-1 infection to the development of clinical AIDS and death. The isolated nucleic acid molecule encoding CCR2-64I and the establishment of cell lines that express CCR2-64I provide valuable tools for ongoing research on HIV infection. Additionally, diagnostic methods for analyzing the allelic frequency of CCR2 wild-type and 64I genes are included in her patent. Antibodies that bind to CCR2-64I, CCR2-64I variants, and CCR2 binding agents represent potential anti-HIV agents.
Career Highlights
Mary Carrington works for the United States of America, as represented by the Secretary, Department of Health and Human Services. Her career has been marked by a commitment to advancing medical research and improving health outcomes for individuals affected by HIV.
Collaborations
Throughout her career, Mary has collaborated with esteemed colleagues such as Stephen James O'Brien and Michael C Dean. These collaborations have furthered her research and contributed to the scientific community's understanding of HIV.
Conclusion
Mary Carrington's innovative work in the field of HIV research highlights the importance of genetic factors in disease progression. Her contributions continue to pave the way for advancements in medical science and potential therapeutic interventions.