Company Filing History:
Years Active: 1998-1999
Title: Mary C Oldenburg: Innovator in Nucleic Acid Detection
Introduction
Mary C Oldenburg is a prominent inventor based in Madison, WI (US). She has made significant contributions to the field of molecular biology, particularly in the detection and identification of nucleic acid variants. With a total of 2 patents, her work has advanced the understanding of genetic mutations and their implications.
Latest Patents
Oldenburg's latest patents include "Rapid detection and identification of nucleic acid variants" and "Cleavase fragment length polymorphism." The first patent relates to methods for cleaving a nucleic acid cleavage structure in a site-specific manner. It utilizes enzymes, including 5' nucleases and 3' exonucleases, to screen for known and unknown mutations in nucleic acids. This invention allows for the identification of genetic mutations and the detection of bacterial and viral strains in a sample. The second patent discloses a novel method of detection for specific nucleic acid sequences, employing a cleaving enzyme with 5' nuclease activity that does not interfere with nucleic acid synthesis.
Career Highlights
Mary C Oldenburg has worked at Third Wave Technologies, Inc., where she has been able to apply her innovative ideas in a collaborative environment. Her work has been instrumental in developing technologies that enhance the accuracy and efficiency of nucleic acid detection.
Collaborations
Throughout her career, Oldenburg has collaborated with notable colleagues, including James E Dahlberg and Victor I Lyamichev. These partnerships have contributed to the advancement of her research and the successful development of her patents.
Conclusion
Mary C Oldenburg is a trailblazer in the field of nucleic acid detection, with her patents paving the way for future innovations in genetic research. Her contributions continue to impact the scientific community and enhance our understanding of genetic variations.