Company Filing History:
Years Active: 2001-2012
Title: The Innovative Contributions of Mary Ann D. Brow
Introduction
Mary Ann D. Brow, based in Madison, WI, is a prolific inventor with a remarkable portfolio that includes 32 patents. Her work primarily focuses on the detection and characterization of nucleic acids, providing significant advancements in the field of molecular biology and diagnostics.
Latest Patents
Among her latest inventions is a groundbreaking patent titled "Detection of nucleic acids by multiple sequential invasive cleavages." This invention encompasses methods for detecting and characterizing nucleic acid sequences, including their variations. It introduces a unique approach to forming and cleaving nucleic acid cleavage structures in a site-specific manner using the structure-specific nuclease activity of various enzymes. This method enhances the ability to indicate the presence of specific nucleic acid sequences and provides techniques for separating nucleic acid molecules based on charge. Additionally, the invention offers sensitive and specific methods for detecting human cytomegalovirus nucleic acid in biological samples.
Another notable patent by Brow is focused on "Methods for modifying an oligonucleotide," which involves mechanisms for cleaving nucleic acid structures site-specifically. Through the use of 5' nucleases and 3' exonucleases, this invention allows for the detection and identification of nucleic acids derived from microorganisms, thus facilitating the identification of bacterial and viral pathogens in samples.
Career Highlights
Mary Ann D. Brow has made substantial contributions throughout her career, particularly while working at Third Wave Technologies, Inc. Her innovative mindset has significantly enhanced the methods of nucleic acid detection, marking her as a pivotal figure in the life sciences sector.
Collaborations
Throughout her career, Brow has collaborated with esteemed colleagues, including Victor I. Lyamichev and James E. Dahlberg. These collaborations have further propelled her research forward, reflecting the importance of teamwork in advancing scientific knowledge and innovation.
Conclusion
Mary Ann D. Brow's contributions to the field of nucleic acid detection and characterization stand as a testament to her inventive spirit and expertise. With 32 patents to her name, she continues to push the boundaries of science, providing tools that have the potential to revolutionize diagnostics and molecular biology. Her work not only enhances our understanding of genetic materials but also underscores the vital role of innovation in the medical and scientific communities.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.