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Marvin R Brown

This inventor holds 12 USPTO granted patents. Top assignees: The Salk Institute, University of California. Active years: 1978-1994.

USPTO Granted Patents = 12

% Patents Active = 100.0

Average Co-Inventor Count = 3.4

ph-index = 10

Forward Citations = 249(Granted Patents)

Location History:

La Jolla, CA (US) (1978 - 1982)
San Diego, CA (US) (1979 - 1983)
Del Mar, CA (US) (1983 - 1994)

Company Filing History:

University of California

patents

where one patent can have more than one assignee

Years Active: 1978-1994

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12 patents (USPTO):Sort by Forward CitationsExplore Patents

1. 5328899 - NPY peptide analogs (1994-07-12),

2. 5026685 - NPY peptide analogs (1991-06-25),

3. 4605642 - CRF antagonists (1986-08-12),

4. 4530838 - Synthetic calcitonin-gene-related peptides for lowering blood pressure (1985-07-23),

5. 4428942 - Analogs of somatostatin (1984-01-31),

6. 4393050 - Analogs of extended N-terminal somatostatin (1983-07-12),

7. 4372884 - Pharmaceutically active peptides (1983-02-08),

8. 4331661 - Bombesin analogs (1982-05-25),

9. 4211693 - Peptides with para-substituted phenylalanine (1980-07-08),

10. 4207311 - Peptides having analgesic and thermoregulative properties (1980-06-10),

11. 4133782 - Somatostatin analogs with dissociated biological activities (1979-01-09),

12. 4105603 - Peptides which effect release of hormones (1978-08-08),

Title: Marvin R. Brown: Innovator in Neuropeptide Research

Introduction

Marvin R. Brown is a distinguished inventor based in Del Mar, California, known for his significant contributions to the field of neuropeptide research. With a total of 12 patents to his name, he has made remarkable advancements in understanding and utilizing neuropeptides for medical applications.

Latest Patents

One of Marvin R. Brown's latest patents focuses on NPY peptide analogs. Human Neuropeptide Y (NPY) has the formula: H-Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr-NH.sub.2. Notably, porcine and rat NPY share the same sequence, differing only at the 17-position where Leu replaces Met. Additionally, porcine PYY is homologous, having 11 different residues. The NPY analogs and N-terminally-shortened fragments, such as NPY(18-36), can contain specific D-isomer substitutions for naturally occurring residues. These compounds, when dispersed in a pharmaceutically acceptable carrier, can be administered to mammals, including humans, to significantly lower blood pressure over an extended period or to counteract hypertension.

Career Highlights

Throughout his career, Marvin R. Brown has worked with prestigious institutions, including the Salk Institute and the University of California. His research has paved the way for innovative treatments targeting hypertension and related health issues.

Collaborations

Marvin has collaborated with notable colleagues such as Jean E. Rivier and Wylie W. Vale, Jr., contributing to the advancement of neuropeptide research.

Conclusion

Marvin R. Brown's work in neuropeptide research has led to significant innovations that hold promise for medical applications, particularly in managing blood pressure. His contributions continue to impact the field positively.

Profile summary based on public USPTO records.

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