Company Filing History:
Years Active: 1997-2019
Title: The Innovations of Marvin P. Wickens: A Pioneer in Poly(UG) Polymerase Research
Introduction
Marvin P. Wickens, based in Madison, Wisconsin, has made significant contributions to the field of molecular biology, particularly in the area of RNA research. With a remarkable portfolio of 10 patents, his innovative work has advanced our understanding of RNA synthesis and manipulation.
Latest Patents
One of Wickens' latest patents focuses on "Poly(UG) polymerase, constructs, and methods of making and using the same." This invention discusses methods, kits, and compositions related to poly(UG) polymerases, where a method includes contacting an RNA substrate with a poly(UG) polymerase. The intent is to allow the polymerase to add a poly(UG) sequence to the RNA substrate over varying periods, ranging from one second to 28 days. The poly(UG) polymerase can be identified as RDE-3.
Another notable patent concerns "RNA monomers containing 0-acetal levulinyl ester groups and their use in RNA microarrays." This invention features RNA monomers with O-acetal levulinyl protecting groups at the ribose moiety's 2' and/or 5'-hydroxy functionalities. It details the incorporation of these monomers into oligoribonucleotides or RNA polynucleotides, providing methods for synthesis, deprotection, and eventual application in light-directed RNA microarray synthesis.
Career Highlights
Throughout his career, Wickens has worked with esteemed organizations including the Wisconsin Alumni Research Foundation and the Royal Institution for the Advancement of Learning at McGill University. These establishments have provided fertile ground for his research and innovation, facilitating the development and application of his groundbreaking inventions.
Collaborations
Wickens has collaborated with notable figures in the scientific community, including Stanley Fields and Roy Parker. Their collective expertise and shared vision in molecular biology have undoubtedly propelled their research efforts and contributed to significant advancements in the field.
Conclusion
Marvin P. Wickens stands out as an influential inventor whose work continues to shape the landscape of RNA research. His latest patents reflect a remarkable depth of knowledge and innovation, solidifying his legacy in the scientific community. Through his collaborations and career achievements, Wickens exemplifies the power of persistence and creativity in driving scientific progress.
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