Company Filing History:
Years Active: 2016
Title: Martina Hasova: Innovator in Hyaluronic Acid Derivatives
Introduction
Martina Hasova is a notable inventor based in Letohrad, Czech Republic. She has made significant contributions to the field of biochemistry, particularly in the development of hyaluronic acid derivatives. Her innovative work has implications for various applications, including tissue engineering and drug delivery systems.
Latest Patents
Martina Hasova holds a patent for a hyaluronic acid derivative, which includes a method of preparation and modification. The invention focuses on the preparation and use of α,β-unsaturated aldehyde of hyaluronan, featuring a double bond in positions 4 and 5, along with an aldehydic group in position 6 of the glucosamine part of the polysaccharide. The preparation method involves dehydration of hyaluronan, which can be achieved either in solution or through heating in a solid state without solvents or additives. This derivative allows for the stabilization of conjugates of hyaluronan with amino compounds, enabling effective immobilization of compounds containing amino groups under physiological conditions. The invention also facilitates the creation of crosslinked hyaluronan derivatives when using diamines or compounds with multiple amino groups.
Career Highlights
Martina Hasova is currently associated with Contipro Biotech S.r.o., where she continues her research and development efforts. Her work has garnered attention for its potential to enhance the effectiveness of biologically active substance carriers and its relevance in tissue engineering.
Collaborations
Martina collaborates with esteemed colleagues, including Radovan Buffa and Petra Sedova, who contribute to her research endeavors and the advancement of their shared goals in biochemistry.
Conclusion
Martina Hasova's innovative work in hyaluronic acid derivatives showcases her commitment to advancing biochemistry and its applications. Her contributions are paving the way for new solutions in tissue engineering and drug delivery systems.