Inventors with similar research interests:
Location History:
- Alischwil, CH (2013)
- Allschwil, CH (2003 - 2023)
Company Filing History:
Years Active: 2003-2025
Areas of Expertise:
Title: Innovations of Martin Bolli in the Field of Pharmaceutical Patents
Introduction
Martin Bolli, an esteemed inventor based in Allschwil, Switzerland, has made significant contributions to the pharmaceutical industry, holding an impressive total of 56 patents. His work primarily focuses on innovative compounds and their therapeutic applications, demonstrating his dedication to improving healthcare outcomes.
Latest Patents
Among his latest inventions is a groundbreaking patent concerning the combination of a 4-pyrimidinesulfamide derivative with an SGLT-2 inhibitor for the treatment of endothelin-related diseases. The compound, aprocitentan, is identified by its chemical structure: {5-(4-bromo-phenyl)-6-[2-(5-bromo-pyrimidin-2-yloxy)-ethoxy]-pyrimidin-4-yl}-sulfamide. This invention highlights its utility as an endothelin receptor antagonist in combination with the SGLT-2 inhibitor. Furthermore, it encompasses pharmaceutical compositions that contain both aprocitentan and the SGLT-2 inhibitor, including various crystalline forms of aprocitentan. Another patent asserts the combination of aprocitentan with other active ingredients for treating endothelin-related diseases, integrating its use with therapeutic agents such as angiotensin receptor blockers and thiazide-like diuretics.
Career Highlights
Martin Bolli has significantly impacted the pharmaceutical landscape through his work at respected companies, including Actelion Pharmaceuticals Ltd and Idorsia Pharmaceuticals Ltd. His career has been marked by a commitment to research and development, where he has pioneered novel solutions in drug design and treatment protocols.
Collaborations
Throughout his professional journey, Martin Bolli has collaborated with notable colleagues, including Boris Mathys and Claus Mueller. These partnerships have fostered a collaborative environment, driving innovation and enhancing the effectiveness of their pharmaceutical endeavors.
Conclusion
In summary, Martin Bolli's extensive patent portfolio and collaborative work in the pharmaceutical industry underscores his significant role as an innovator. His contributions to the development of new therapeutic agents, particularly in combating endothelin-related diseases, continue to propel advancements in healthcare, demonstrating the importance of innovation in the pharmaceutical realm.
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