This inventor holds 3 USPTO granted patents. Top assignees: Health Research, Inc., Rensselaer Polytechnic Institute. Active years: 1991-2005.
Company Filing History:
Years Active: 1991-2005
Title: Marlene Belfort: Innovator in Genetic Engineering and Bioseparations
Introduction
Marlene Belfort is a prominent inventor based in Slingerlands, NY (US). She has made significant contributions to the field of genetic engineering and bioseparations. With a total of 3 patents, her work has advanced the understanding and application of self-cleaving inteins in protein purification.
Latest Patents
Marlene Belfort's latest patents include innovative technologies such as "Genetic System and Self-Cleaving Inteins Derived Therefrom," "Bioseparations and Protein Purification Employing Same," and "Methods for Determining Critical, Generalizable Amino Acid Residues for Varying Intein Activity." These patents describe a self-cleaving element derived from a naturally occurring protein splicing element, known as intein. Through protein engineering and random mutagenesis, she has developed mini-inteins with enhanced splicing activity, which have significant applications in the purification of proteins, including toxic proteins. Her work provides new insights into the structural and functional roles of conserved residues in protein splicing.
Career Highlights
Throughout her career, Marlene has worked with notable organizations such as Health Research, Inc. and Rensselaer Polytechnic Institute. Her research has focused on the efficacy of antimicrobial agents that inhibit intein function, utilizing genetic screens to monitor the function of protein inteins and isolate conditional mutants.
Collaborations
Marlene has collaborated with esteemed colleagues, including Georges Belfort and Vicky Derbyshire, contributing to the advancement of her research and innovations in the field.
Conclusion
Marlene Belfort's contributions to genetic engineering and bioseparations have paved the way for new methodologies in protein purification and antimicrobial research. Her innovative patents and collaborative efforts continue to influence the scientific community.