Location History:
- Amsterdam, NL (2001)
- Amersterdam, NL (2001)
Company Filing History:
Years Active: 2001
Title: Innovations of Markus Peter Wilhelmus Einerhand
Introduction
Markus Peter Wilhelmus Einerhand is a notable inventor based in Amsterdam, Netherlands. He has made significant contributions to the field of genetic modification and gene therapy. With a total of two patents to his name, his work focuses on advancing medical science through innovative techniques.
Latest Patents
Einerhand's latest patents include groundbreaking research on the genetic modification of primate hemopoietic repopulating stem cells. This invention involves the transduction of pluripotent hemopoietic stem cells of primates using a recombinant adeno-associated virus (AAV). The genomic structure of the recombinant AAV contains a DNA sequence flanked by inverted terminal repeats (ITR) of AAV. This DNA sequence typically includes regulatory sequences functional in hemopoietic cells, which control the expression of therapeutic proteins or RNAs when introduced into these cells. Examples of such DNA sequences include the human lysosomal glucocerebrosidase gene and the human multidrug resistance gene I (MDRI). This invention aims to provide effective gene therapy for primates, particularly humans.
Another significant patent by Einerhand is related to a conditional replication and expression system. This invention utilizes conditionally replicating recombinant nucleic acid molecules for the expression of foreign proteins. The system is exemplified by a conditionally replicating recombinant nucleic acid molecule that encodes the AAV capsid proteins. It also encompasses methods for packaging recombinant AAV nucleic acid molecules into AAV capsids, along with the development of packaging cell lines that express both the AAV rep and cap genes.
Career Highlights
Einerhand is currently associated with Introgene B.V., where he continues to push the boundaries of genetic research. His work has the potential to revolutionize gene therapy and improve treatment options for various diseases.
Collaborations
One of his notable collaborators is Domenico Valerio, with whom he has worked on various projects related to his patents.
Conclusion
Markus Peter Wilhelmus Einerhand is a prominent figure in the field of genetic modification and gene therapy. His innovative patents reflect his commitment to advancing medical science and improving therapeutic techniques.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.