Location History:
- Ubandale, IA (US) (1992 - 1994)
- Urbandale, IA (US) (1999)
Company Filing History:
Years Active: 1992-1999
Title: The Innovations of Mark W. Welter in Swine Vaccine Technology
Introduction
Mark W. Welter, an accomplished inventor based in Urbandale, IA, has made significant contributions to the field of veterinary science through his innovative work on vaccines for swine. With three patents to his name, Welter's research primarily focuses on the identification and development of antigens that can lead to effective vaccination against infectious diseases in pigs.
Latest Patents
Among Welter's notable patents is the invention related to the Isospora suis sporozoite antigen. This innovative approach utilizes a swine testicular cell line, which facilitates the production of sporozoites and merozoites suitable for vaccination. His research has resulted in the creation of neutralizing antibodies against Isospora suis sporozoites, which inhibit the infectivity of sporozoites. Furthermore, he identified a sporozoite attachment protein and successfully cloned the cDNA encoding part of this protein. This discovery includes two regions with repeated amino acid sequences, potentially valuable for future vaccine development.
Another significant patent is focused on Type-C rotavirus cultures. Welter's work improved the propagation of Type-C rotavirus in swine testicular cells with reduced concentrations of proteolytic enzymes. This advancement allows for the subsequent production of antigens and antisera, essential for diagnostic kits and killed vaccines to prevent Type-C rotavirus infections. His innovative propagation methods may also lead to the development of modified live virus vaccines targeting this infection.
Career Highlights
Welter's dedication to veterinary microbiology is evident in his patents and ongoing research activities. Working at Ambico, Inc., he has established a reputation as an expert in his field, driving innovations that improve the health and productivity of swine.
Collaborations
Throughout his career, Welter has collaborated with several notable colleagues, including C. Joseph Welter and David M. Chambers. These partnerships have played a crucial role in his innovative developments and the successful application of his patented technologies in the veterinary field.
Conclusion
Mark W. Welter stands out as a significant figure in the arena of swine health innovation. His contributions through patents not only demonstrate his expertise but also reflect a commitment to improving agricultural practices and animal welfare. With ongoing research and collaborations, he continues to pave the way for advancements in vaccine technologies for swine, promising a healthier future for the livestock industry.