Location History:
- Doylestown, PA (US) (1990 - 1994)
- Carmel, IN (US) (1997 - 1999)
Company Filing History:
Years Active: 1990-1999
Title: The Innovations of Mark W Riemen
Introduction
Mark W Riemen is a notable inventor based in Doylestown, PA (US). He has made significant contributions to the field of biotechnology, particularly in the development of modified proteins for therapeutic applications. With a total of 7 patents to his name, Riemen's work has had a considerable impact on medical research and treatment options.
Latest Patents
One of Riemen's latest patents involves the modification of pseudomonas exotoxin PE.sub.40. This modification includes deleting or substituting one or more cysteine residues, resulting in a protein that can be incorporated into a fusion protein with TGF.alpha. The resulting fusion protein exhibits altered biological activities compared to unmodified TGF.alpha.-PE.sub.40, including decreased cell killing activity and increased receptor-binding activity. Another patent focuses on the same modified pseudomonas exotoxin PE.sub.40, highlighting its potential for hybridization with TGF.alpha. to achieve similar altered biological activities.
Career Highlights
Mark W Riemen is currently associated with Merck & Company, Inc., where he continues to innovate and contribute to the field of biotechnology. His work at Merck has allowed him to collaborate with leading experts and researchers in the industry, further enhancing his contributions to medical science.
Collaborations
Some of Riemen's notable coworkers include Allen I Oliff and David C Heimbrook. Their collaborative efforts have played a crucial role in advancing research and development in their respective fields.
Conclusion
Mark W Riemen's innovative work in modifying pseudomonas exotoxin PE.sub.40 showcases his dedication to advancing medical research. His contributions have the potential to lead to significant improvements in therapeutic applications, making him a key figure in the biotechnology industry.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.