Villanova, PA, United States of America

Mark Stearns



Average Co-Inventor Count = 3.0

ph-index = 1

Forward Citations = 2(Granted Patents)


Company Filing History:


Years Active: 2010-2012

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5 patents (USPTO):

Title: **Innovative Contributions of Inventor Mark Stearns**

Introduction

Mark Stearns, an accomplished inventor based in Villanova, Pennsylvania, has made significant advancements in the medical field, particularly in prostate cancer detection and treatment. With a total of five patents to his name, Stearns has focused his research on DNA microarray proteomics platforms, yielding crucial insights into gene expression related to prostate cancer.

Latest Patents

Among Mark Stearns' notable patents is a groundbreaking formulation referred to as "Prostate cancer-related compositions, methods and kits based on DNA microarray proteomics platforms." This invention details novel nucleic acids that encode the mammalian PCADM-1 gene, as well as the proteins associated with it. These expressions have been found to increase in certain ailments, especially prostate cancer. Stearns' work includes developing methods for detecting and treating prostate cancer through modulation of PCADM-1 expression and the activity of PCADM-1 polypeptides. Additionally, his inventions encompass new assays designed to identify DNA-binding proteins, along with the specific double-stranded oligonucleotide sequences that interact with them. A further highlight of his patents is the introduction of DNAZYMs, or DNA enzymes, which target the PCADM-1 mRNA to inhibit its gene expression, presenting a promising approach to destroying tumor cells and tissue.

Career Highlights

Mark Stearns has held significant roles in organizations that promote health education and research. He has worked with the Philadelphia Health and Education Corporation, contributing to his innovative approach to health sciences. His experiences have not only enhanced his own knowledge but have also positioned him as a significant contributor to the field of cancer research.

Collaborations

Throughout his career, Mark Stearns has collaborated with esteemed colleagues, including Youji Hu and Min Wang, facilitating innovative research efforts and enhancing the impact of his work in biochemical innovation. These collaborations have played a crucial role in advancing the understanding of prostate cancer and developing effective treatments.

Conclusion

Mark Stearns is a remarkable inventor whose work and patents are making significant strides in medical research, specifically in the fight against prostate cancer. His innovative methodologies not only provide new avenues for detection but also offer potential treatments that could revolutionize how this disease is managed. As the research progresses, Stearns' contributions are sure to leave a lasting impact on the field of oncology and beyond.

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