Company Filing History:
Years Active: 1987-2008
Title: Mark Sonders: Innovator in Biogenic Amine Receptors
Introduction
Mark Sonders is a notable inventor based in Portland, OR (US). He has made significant contributions to the field of biogenic amine receptors, holding a total of 2 patents. His work focuses on the isolation and characterization of mammalian trace amine receptor proteins, which have important implications in pharmacological screening and mental health treatment.
Latest Patents
One of Sonders' latest patents is titled "Nucleic acids encoding a biogenic amine receptor." This invention relates to novel mammalian biogenic amine receptor proteins and the genes that encode them. It provides isolated complementary DNA copies of mRNA corresponding to rat and human homologues of a mammalian trace amine receptor gene. The invention also includes recombinant expression constructs capable of expressing these genes in transformed prokaryotic and eukaryotic cells. Additionally, it offers methods for screening compounds that can bind to these receptor proteins, enhancing pharmacological screening methods.
Another significant patent is "Sigma brain receptor ligands and their use." This patent describes 1,3-disubstituted-guanidines, which are highly selective ligands for sigma brain receptors. These ligands are useful in diagnosing and treating hallucination-associated psychotic mental illnesses and chronic mental depression. The patent also discusses the use of tritium-labeled 1,3-di-(o-tolyl)-guanidine as a screening tool for compounds with selective sigma receptor binding activity.
Career Highlights
Mark Sonders has worked with various organizations, including the State of Oregon and Oregon Health & Science University. His work has significantly advanced the understanding of biogenic amine receptors and their applications in medicine.
Collaborations
Throughout his career, Sonders has collaborated with notable individuals such as Eckard Weber and John F. Keana. These collaborations have contributed to the development of innovative solutions in the field of biogenic amine receptors.
Conclusion
Mark Sonders is a distinguished inventor whose work in biogenic amine receptors has paved the way for advancements in pharmacological screening and mental health treatment. His contributions continue to impact the scientific community and improve therapeutic approaches.