This inventor holds 1 USPTO granted patent. Top assignee: Cell Signaling Technology, Inc.. Active years: 2011.
Company Filing History:
Years Active: 2011
Title: Mark Livingstone: Innovator in ATR Kinase Detection
Introduction
Mark Livingstone, an esteemed inventor based in Montreal, Canada, has made significant contributions to the field of biotechnology through his innovative research and patented technology. He is recognized for his work on developing reagents that advance the detection of phosphorylated ATR kinase, which plays a crucial role in cellular responses to DNA damage.
Latest Patents
Livingstone holds one patent titled "Reagents for the detection of phosphorylated ATR kinase (Ser 428) and uses thereof." This invention reveals two novel phosphorylation sites in human ATR kinase: serine 428 (Ser428) and serine 2317 (Ser2317). It provides specific reagents, including antibodies and AQUA peptides, that selectively bind to ATR only when phosphorylated at these critical sites. Importantly, these reagents do not bind to ATR when it is not phosphorylated, enabling accurate determination of ATR kinase phosphorylation in biological samples.
Career Highlights
Livingstone is an integral part of the team at Cell Signaling Technology, Inc., where he has been able to channel his expertise into groundbreaking research. His innovative work has not only advanced scientific understanding but also provided new tools for researchers working in the field of cellular biology.
Collaborations
Throughout his career, Livingstone has collaborated with esteemed colleagues such as Hong Ruan and Robert Polakiewicz. These partnerships reflect a commitment to advancing research and sharing knowledge within the scientific community, enhancing the impact of their combined discoveries.
Conclusion
Mark Livingstone's innovations, particularly in the detection of phosphorylated ATR kinase, represent a significant advancement in biotechnology. His patented technology promises to facilitate further research into DNA damage response mechanisms, paving the way for future discoveries in molecular biology and therapeutic development.