Location History:
- Portage, MI (US) (1999)
- Kalamazoo, MI (US) (2004)
Company Filing History:
Years Active: 1999-2004
Title: Mark L Wolfe: Innovator in Ion Channel Research
Introduction
Mark L Wolfe is a distinguished inventor based in Portage, MI (US). He has made significant contributions to the field of cellular ion channel research, holding a total of 3 patents. His work focuses on innovative methods for measuring and manipulating ion channel transmission, which has important implications for drug development.
Latest Patents
Wolfe's latest patents include groundbreaking inventions such as the "Double mutant alpha-7 nicotinic acetylcholine receptor." This invention relates to novel methods for measuring cellular ion channel transmission and methods and compositions useful in the identification of ligand-gated ion channel agonists and modulators. Another notable patent is for a "Protein affecting K.sub.ATP channels," which describes the isolation and identification of a new protein, p56. This protein is useful for identifying drugs that selectively open or close K channels, with a molecular weight of about 56,000 daltons and a specific N-terminal peptide sequence.
Career Highlights
Mark L Wolfe is currently associated with Pharmacia & Upjohn Company, where he continues to advance his research in ion channels. His work has been instrumental in developing new therapeutic strategies for various medical conditions.
Collaborations
Wolfe has collaborated with notable colleagues, including Vincent E Groppi, Jr and Martin R Deibel, Jr. These partnerships have enhanced the scope and impact of his research.
Conclusion
Mark L Wolfe's innovative contributions to ion channel research exemplify the importance of scientific inquiry in developing new medical therapies. His patents reflect a commitment to advancing our understanding of cellular mechanisms and their applications in drug discovery.