Company Filing History:
2 out of 1,324 
1 out of 832,843 Years Active: 1999-2006
Title: Innovations by Mark I Smedley
Introduction
Mark I Smedley is an accomplished inventor based in Foster City, CA (US). He holds a total of 3 patents that focus on the development of microparticles for drug delivery systems. His work has significant implications for the medical field, particularly in the controlled release of biologically active drugs.
Latest Patents
One of his latest patents is the "ICAM-1 formulation having controlled-size microparticles." This invention details a method and system for producing microparticles loaded with biologically active drugs, including proteins such as ICAM-1, for controlled release in the nasal passageway. The method involves introducing a drug/polymer feed solution and an emulsifier into a first mixing chamber to create an emulsion. A cross-linking agent is then mixed with the emulsion under controlled conditions to create the microparticles. The system includes a first mixing chamber for creating the emulsion and a second mixing chamber that receives the emulsion to solidify the microparticles. The formed microparticles are filtered and deaggregated to ensure they can be effectively delivered through the nasal passageway.
Another significant patent is the "System and method for producing drug-loaded microparticles." This patent outlines a similar method and system for creating microparticles loaded with biologically active drugs. The process is designed to ensure that the microparticles can be effectively used for drug delivery in a controlled manner.
Career Highlights
Mark I Smedley has worked with notable organizations, including SRI International. His experience in these companies has contributed to his expertise in the field of drug delivery systems and microparticle technology.
Collaborations
Throughout his career, Mark has collaborated with professionals such as David C Bomberger and Paul G Catz. These collaborations have likely enriched his work and contributed to the advancements in his inventions.
Conclusion
Mark I Smedley is a notable inventor whose work in microparticle technology has the potential to revolutionize drug delivery systems. His innovative patents reflect his commitment to advancing medical science and improving patient care.