Mark Henry Pausch

Title: Mark Henry Pausch: Innovator in G-Protein Coupled Receptor Research

Introduction

Mark Henry Pausch is a notable inventor based in Robbinsville, NJ (US). He has made significant contributions to the field of biotechnology, particularly in the area of G-protein coupled receptors. With a total of 12 patents to his name, Pausch's work has advanced our understanding of receptor biology and its applications in therapeutic development.

Latest Patents

Pausch's latest patents include groundbreaking inventions such as "Heterologous G protein coupled receptors expressed in yeast, their fusion with G proteins and use thereof in bioassay." This patent focuses on expression vectors and yeast cells that contain a heterologous G protein-coupled receptor gene, which enhances sensitivity to receptor activation. Another significant patent is "Murine genomic polynucleotide sequence encoding a G-protein coupled receptor and methods of use therefor." This invention relates to a newly identified murine genomic polynucleotide that encodes an ortholog of the human P2T receptor, which is expressed at high levels in the central nervous system. It also explores the potential therapeutic applications of compounds that may act as agonists, antagonists, or inhibitors of the P2T receptor.

Career Highlights

Throughout his career, Mark Henry Pausch has worked with prominent companies in the biotechnology sector, including American Cyanamid Company and BASF Aktiengesellschaft. His work has been instrumental in developing innovative solutions that bridge the gap between basic research and practical applications in medicine.

Collaborations

Pausch has collaborated with notable colleagues such as John Richard Hadcock and Bradley Alton Ozenberger. These partnerships have fostered a collaborative environment that has led to significant advancements in their respective fields.

Conclusion

Mark Henry Pausch's contributions to the field of G-protein coupled receptors have established him as a leading inventor in biotechnology. His innovative patents and collaborations continue to influence research and development in therapeutic applications.