Mark G Frei

This inventor holds 77 USPTO granted patents and 3 published patent applications, plus 4 CIPO patents and 9 EPO patents, primarily in Cardiac Signal Analysis (CPC class A61B). Top assignees: Flint Hills Scientific, LLC, Medtronic, Inc., Cyberonics, Inc.. Active years: 1999-2025.

USPTO Granted Patents = 77 (Patent Applications = 3)

% Patents Active = 80.5

CIPO Patents = 4

EPO Patents = 9 (Patent Applications = 3)

Average Co-Inventor Count = 2.6

ph-index = 33

Forward Citations = 6,624(Granted Patents)

Forward Citations (Not Self Cited) = 5,775(Dec 10, 2025)

Inventors with similar research interests:

Location History:

Lawrence, KS (US) (1999 - 2021)
Oviedo, FL (US) (2012 - 2021)
Leawood, KS (US) (2016 - 2021)

Company Filing History:

39 out of 132

Flint Hills Scientific, LLC

Plint Hills Scientific LLC

patent

6. 7 out of 834,411

Other

patents

where one patent can have more than one assignee

Years Active: 1999-2025

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Areas of Expertise:

Cardiac Data

Seizure Detection

Vagal Nerve Stimulation

Heart Rate Validation

Neurological Activity

Signal Analysis

Medical Device

Event Length Determination

Therapy Efficacy

Dynamic Stimulation

Quantitative Logging

Failure Detection

77 patents (USPTO):Sort by Forward CitationsExplore Patents

1. 12310740 - Detecting or validating a detection of a state change from a template of heart rate derivative shape or heart beat wave complex (2025-05-27),

2. 12178594 - Detecting or validating a detection of a state change from a template of heart rate derivative shape or heat beat wave complex (2024-12-31),

3. 11185695 - Method and system for logging quantitative seizure information and assessing efficacy of therapy using cardiac signals (2021-11-30),

4. 11179094 - Detecting or validating a detection of a state change from a template of heart rate derivative shape or heart beat wave complex (2021-11-23),

5. 11026622 - State change indication by matching instantaneous heart rate shape to shape change template (2021-06-08),

6. 10130294 - Detecting or validating a detection of a state change from a template of heart rate derivative shape or heart beat wave complex (2018-11-20),

7. 9974956 - Validity test adaptive constraint modification for cardiac data used for detection of state changes (2018-05-22),

8. 9750448 - Method, apparatus and system for validating and quantifying cardiac beat data quality (2017-09-05),

9. 9700256 - Algorithm for detecting a seizure from cardiac data (2017-07-11),

10. 9659216 - Method, computer program, and system for automated real-time signal analysis for detection, quanitification, and prediction of signal changes (2017-05-23),

11. 9592003 - Vagal nerve stimulation techniques for treatment of epileptic seizures (2017-03-14),

12. 9468761 - Validity test adaptive constraint modification for cardiac data used for detection of state changes (2016-10-18),

13. 9451894 - Detecting or validating a detection of a state change from a template of heart rate derivative shape or heart beat wave complex (2016-09-27),

14. 9265433 - State change indication by matching instantaneous heart rate shape to shape change template (2016-02-23),

15. 9241647 - Algorithm for detecting a seizure from cardiac data (2016-01-26),

Title: The Inventor Mark G Frei: Pioneering Innovations in Lawrence, KS

Introduction: Mark G Frei is a distinguished inventor based in Lawrence, Kansas, known for his groundbreaking contributions to various fields through his innovative creations.

Latest Patents: Mark G Frei holds several patents in the areas of renewable energy technologies, sustainable agriculture practices, and advanced medical devices, showcasing his versatility and forward-thinking approach.

Career Highlights: With a career spanning over two decades, Mark G Frei has consistently pushed the boundaries of traditional thinking, leading to the development of cutting-edge solutions that have positively impacted industries worldwide.

Collaborations: Throughout his career, Mark G Frei has collaborated with leading research institutions, universities, and companies to bring his inventions to life, fostering a culture of innovation and collaboration in the process.

Conclusion: Mark G Frei's passion for innovation and his relentless pursuit of excellence have solidified his reputation as a visionary inventor, shaping the future of technology and leaving a lasting legacy in the world of inventions.