Location History:
- Manchester, GB (2004)
- Blackley, GB (2007)
Company Filing History:
Years Active: 2004-2007
Title: Mark Edward Douglas: Innovator in Oligonucleotide Synthesis
Introduction
Mark Edward Douglas is a notable inventor based in Blackley, GB. He has made significant contributions to the field of oligonucleotide synthesis, holding 2 patents that showcase his innovative processes.
Latest Patents
His latest patents include a process for the preparation of phosphorothioate oligonucleotides. This process involves assembling an oligonucleotide bound to a solid support in the presence of acetonitrile. Prior to cleaving the oligonucleotide from the solid support, the acetonitrile is removed. The method is particularly suited for large-scale synthesis of nucleotides. The acetonitrile can be removed from the solid support by drying or washing with solvents, with preferred washing solvents comprising trialkylamines.
Career Highlights
Mark Edward Douglas is associated with Avecia Limited, where he applies his expertise in oligonucleotide synthesis. His work has contributed to advancements in the field, particularly in the efficient production of nucleotides.
Collaborations
He has collaborated with notable coworkers such as Ben James Mellor and Donald Alfred Wellings, further enhancing the innovative environment in which he works.
Conclusion
Mark Edward Douglas is a prominent figure in the field of oligonucleotide synthesis, with a focus on improving processes for large-scale production. His contributions continue to impact the industry positively.