Company Filing History:
Years Active: 2016-2023
Title: Mark Debenedette: Innovator in Dendritic Cell Therapy
Introduction
Mark Debenedette, an accomplished inventor based in Durham, NC, has made significant strides in the field of immunology with three patents to his name. His innovative work focuses on dendritic cell therapy, which has potential implications for treating various diseases by enhancing the immune response.
Latest Patents
Debenedette's latest patents encompass groundbreaking methods and uses for dendritic cell therapy. One of his notable inventions outlines processes for evaluating immune system parameters to identify patients likely to experience favorable treatment outcomes. The invention details methods for treating human patients with dendritic cell therapy by measuring specific treatment indicators and administering therapy based on those measurements.
Another remarkable patent describes the preparation and use of mature dendritic cell compositions. This innovation involves signaling isolated immature dendritic cells (iDCs) and utilizing a two-step process that results in CCR7-mature dendritic cells with enhanced immunostimulatory properties. The enriched populations of dendritic cells developed through this method are designed to increase IL-12 secretion and decrease IL-10 secretion, offering a promising avenue for therapeutic applications.
Career Highlights
Throughout his career, Mark Debenedette has worked with several esteemed companies, including Argos Therapeutics, Inc. and Coimmune, Inc. His experience in these organizations has undoubtedly contributed to his inventive work in dendritic cell therapy and other immunological advancements.
Collaborations
During his journey as an inventor, Debenedette has collaborated with notable colleagues such as Don Healey and Irina Tcherepanova. Their collective efforts in research and development have fostered an environment of innovation and discovery in the field of immunotherapy.
Conclusion
Mark Debenedette's contributions to dendritic cell therapy highlight his commitment to enhancing medical treatments through innovative inventions. His patents reflect a deep understanding of immunological processes and demonstrate a clear path toward improving patient outcomes in the medical field. As the landscape of biotechnology continues to evolve, Debenedette's work will undoubtedly leave a lasting impression on the future of immunotherapy.