Houston, TX, United States of America

Mark A Pershouse

USPTO Granted Patents = 6 

 

Average Co-Inventor Count = 5.0

ph-index = 5

Forward Citations = 78(Granted Patents)


Company Filing History:


Years Active: 2001-2014

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6 patents (USPTO):Explore Patents

Title: Innovator Mark A Pershouse: Pioneering Cancer Research

Introduction

Mark A Pershouse is a notable inventor and researcher based in Houston, Texas. With a total of six patents to his name, he has made significant contributions to the field of cancer research, particularly in the identification of tumor suppressor genes.

Latest Patents

Among his most recent inventions is the groundbreaking tumor suppressor designated TS10Q23.3. This innovation addresses a specific region of chromosome 10 (10q23.3), which has been linked to the presence of tumor suppressor genes involved in gliomas and various other human cancers. Mark identified a gene within this region that encodes a novel 47 kD protein. Remarkably, this protein has a domain that matches the conserved catalytic domain found in protein tyrosine phosphatases, suggesting its possible role in critical phosphorylation processes. Further sequence analyses revealed that several exons of this gene were deleted in tumor cell lines. This led to the classification of the gene as a tumor suppressor, with additional studies illustrating mutations in glioma and prostate carcinoma cells. Mark's work has also disclosed methods for diagnosing and treating cancers associated with this significant tumor suppressor.

Career Highlights

Throughout his career, Mark A Pershouse has worked with esteemed institutions, including the University of Texas System. His innovative spirit is reflected in the six patents he holds, all aimed at advancing cancer diagnostics and treatments.

Collaborations

Mark has collaborated with other prominent researchers in his field, including Peter A Steck and Samar A Jasser. These partnerships have fostered an environment of innovation, enabling new discoveries in cancer research and treatment options.

Conclusion

Mark A Pershouse stands out as an influential inventor in the realms of cancer genetics and treatment methodologies. His contributions, especially in the development of the TS10Q23.3 tumor suppressor, hold promise for improving diagnostic and therapeutic approaches to cancer, showcasing the importance of innovation in the medical field.

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