This inventor holds 2 USPTO granted patents and 10 published patent applications and 1 EPO patent. Top assignee: National Institute of Health and Medical Research. Active years: 2015-2023.
Company Filing History:
Years Active: 2015-2023
Title: Marisol Corral-Debrinski: Innovator in Mitochondrial Protein Importation
Introduction
Marisol Corral-Debrinski is a prominent inventor based in Montreuil, France. She has made significant contributions to the field of mitochondrial protein importation, holding 2 patents that focus on innovative methods for delivering proteins to mitochondria in mammalian cells.
Latest Patents
Her latest patents include groundbreaking work on the importation of mitochondrial proteins using an enhanced allotopic approach. One patent describes an expression vector that contains appropriate mitochondrion-targeting sequences (MTS) and 3'UTR sequences, which facilitate the efficient and stable delivery of mRNA encoding a protein to the mitochondrion. This method allows for the translocation of a mature functional protein into the mitochondria, addressing defects in mitochondrial function. Another patent emphasizes the importance of mRNA sorting to the mitochondrial surface, demonstrating that selecting the right MTS and 3'UTR sequences is crucial for successful allotopic expression.
Career Highlights
Throughout her career, Marisol has worked with esteemed organizations such as the Institut National de la Santé et de la Recherche Médicale and Inserm. Her research has significantly advanced the understanding of mitochondrial protein importation and its therapeutic applications.
Collaborations
Marisol has collaborated with notable colleagues, including Jose-Alain Sahel and Valerie Kaltimbacher, contributing to the advancement of her research and innovations in the field.
Conclusion
Marisol Corral-Debrinski's work in mitochondrial protein importation showcases her dedication to scientific innovation and her impact on medical research. Her patents represent a significant step forward in addressing mitochondrial dysfunction, highlighting her role as a leading inventor in this critical area of study.