Company Filing History:
2 out of 75 
1 out of 48 
1 out of 1,974 
Years Active: 2021-2022
Title: The Innovative Contributions of Marion Subklewe
Introduction
Marion Subklewe is a notable inventor based in Munich, Germany. He has made significant contributions to the field of biomedicine, particularly in the development of novel therapeutic molecules. With a total of three patents to his name, Subklewe's work focuses on innovative approaches to cancer treatment.
Latest Patents
One of Subklewe's latest patents is a trispecific molecule that combines specific tumor targeting with local immune checkpoint inhibition. This invention relates to a novel molecule that comprises three binding sites, each with specificity for a tumor cell, an effector cell, and a checkpoint molecule, respectively. Additionally, the invention includes a pharmaceutical composition that utilizes this molecule and outlines its various applications.
Another significant patent involves the administration of a bispecific construct that binds to CD33 and CD3 for the treatment of myeloid leukemia. This invention provides a bispecific construct that includes a first binding domain specifically targeting CD33 and a second binding domain specifically targeting CD3. The method described allows for the administration of this construct for a maximum period of 14 days, followed by a 14-day period without administration. Furthermore, the invention details a method for treating myeloid leukemia using a therapeutically efficient amount of this bispecific construct.
Career Highlights
Throughout his career, Marion Subklewe has worked with prominent organizations, including Amgen Research GmbH and Ludwig-Maximilians-Universität München. His experience in these institutions has allowed him to collaborate on groundbreaking research and development projects.
Collaborations
Subklewe has collaborated with notable colleagues, including Karl-Peter Hopfner and Nadine Magauer. These partnerships have contributed to the advancement of his research and the successful development of his patented inventions.
Conclusion
Marion Subklewe's innovative work in the field of biomedicine has led to the development of important therapeutic molecules aimed at treating cancer. His contributions continue to impact the medical community and offer hope for improved treatment options.