Company Filing History:
4 out of 37 
1 out of 258 
1 out of 1 Years Active: 1992-2010
Title: The Innovative Contributions of Mario J. Feola
Introduction
Mario J. Feola is a notable inventor based in Lubbock, Texas, recognized for his significant contributions to the field of medical technology. With a total of seven patents to his name, Feola has focused on developing innovative methods and compositions that address critical health issues, particularly in the area of blood substitutes.
Latest Patents
Feola's latest patents include groundbreaking methods for treating acute blood loss. His inventions relate to novel methods of using blood substitutes to effectively manage acute blood loss and include pharmaceutical compositions that utilize these substitutes. The blood substitutes he has developed can induce the expression of erythropoietin under normoxic conditions and promote erythropoiesis, which is crucial for patients experiencing significant blood loss. Additionally, his patents detail the use of cross-linked hemoglobin blood substitutes that stabilize HIF-1 alpha expression and down-regulate NF-kappa B. Another significant patent involves ultra-pure hemoglobin solutions, which are designed to be endotoxin-free and serve as effective plasma expanders.
Career Highlights
Throughout his career, Mario J. Feola has worked with prominent organizations such as Biopure Corporation and Texas Tech University Health Sciences Center. His work in these institutions has allowed him to advance his research and develop innovative solutions in the medical field.
Collaborations
Feola has collaborated with esteemed colleagues, including Carl W. Rausch and Jan S. Simoni, to further enhance his research and development efforts. These collaborations have contributed to the successful implementation of his innovative ideas.
Conclusion
Mario J. Feola's contributions to the field of medical technology through his patents and collaborations highlight his commitment to improving healthcare solutions. His innovative methods for treating acute blood loss and developing blood substitutes demonstrate the impact of his work on patient care and medical advancements.