Marina Cella

Title: Marina Cella: Innovator in Biologically Active Antibodies

Introduction

Marina Cella is a prominent inventor based in St. Louis, MO (US). She has made significant contributions to the field of immunology, particularly in the development of biologically active antibodies. Her work has implications for understanding and treating various diseases.

Latest Patents

Marina Cella holds a patent for "Biologically active antibodies recognizing a cell surface molecule selectively expressed on living mouse natural type one (I) interferon producing cells." This patent describes an isolated and characterized monoclonal antibody ('440c') that was prepared by immunizing Wistar/CRL rats subcutaneously with purified rat bone marrow IPC. The process involved fusing popliteal lymph nodes of the rats with SP2/0 myeloma spleen cells and differentially selecting for hybridome supernatants that successfully stain bone marrow-derived IPC and fractions thereof using CD11c+ spleen cells. The patent further details the differential selection for hybridoma supernatants from the CD11c+ spleen cells that successfully stain only CD 11c+/Ly6c+/CD 11b−/B220+ splenocytes to provide the monoclonal antibody.

Career Highlights

Throughout her career, Marina has focused on advancing the understanding of immune responses through her innovative research. Her dedication to her work has led to the successful development of her patented antibody, which is a testament to her expertise in the field.

Collaborations

Marina has collaborated with notable colleagues, including Amanda L Blasius and Marco Colonna. These partnerships have enriched her research and contributed to the advancement of immunological studies.

Conclusion

Marina Cella is a distinguished inventor whose work in biologically active antibodies has the potential to impact medical science significantly. Her innovative approach and collaborative spirit continue to drive advancements in immunology.