Marilyn Khanna

Title: The Innovative Contributions of Marilyn Khanna

Introduction

Marilyn Khanna is a prominent inventor based in Milwaukee, WI (US). She has made significant contributions to the field of molecular biology, particularly in the detection of nucleic acid differences. With a total of 3 patents, her work has implications for cancer research and diagnostics.

Latest Patents

One of her latest patents is focused on high fidelity detection of nucleic acid differences by ligase detection reaction. This innovative method utilizes ligase detection reaction to distinguish minority templates in the presence of an excess of normal templates using a thermostable ligase. The process can be executed with a mutant ligase, thermostable ligase, or a modified oligonucleotide probe. This procedure is particularly beneficial for detecting cancer-associated mutations, providing a quantitative measure of the amount or ratio of the minority template. Another notable patent involves thermostable DNA ligase mutants, which also aims to enhance the detection of cancer-associated mutations through similar methodologies.

Career Highlights

Throughout her career, Marilyn Khanna has worked with various research institutions, including the Cornell Research Foundation Inc. Her innovative approaches have garnered attention in the scientific community, contributing to advancements in genetic research and diagnostics.

Collaborations

Marilyn has collaborated with notable individuals in her field, including Francis Barany and Jianying Luo. These partnerships have further enriched her research and expanded the impact of her inventions.

Conclusion

Marilyn Khanna's contributions to the field of molecular biology through her patents and collaborations highlight her role as an influential inventor. Her work continues to pave the way for advancements in cancer detection and treatment.