Marie-Thérèse Paternostre

Title: Innovations of Marie-Thérèse Paternostre

Introduction

Marie-Thérèse Paternostre, a prominent inventor hailing from Verrières le Buisson, France, has made significant contributions to the field of medicinal chemistry. With a total of two patents to his name, Paternostre's work focuses on the therapeutic applications of novel octapeptide compounds derived from somatostatin. His inventions have the potential to revolutionize treatment for various pathological states involving somatostatin receptors.

Latest Patents

Paternostre's latest patents include groundbreaking octapeptide compounds, one of which is characterized by the general formula (I): H-2-Nal-cyclo(Cys-Tyr-AA-Lys-Val-Cys)-Thr-NH. These compounds demonstrate a strong affinity for specific somatostatin receptor subtypes, making them particularly advantageous for treating diseases associated with these receptors. Furthermore, the physiochemical properties of these octapeptides allow for versatile formulation as pharmaceutical carriers, accentuating their utility in medicament development.

The second patent focuses on another set of novel octapeptide compounds described by the general formula (I): R-AA-cyclo(AA-Tyr-D-Trp-AA-Val-Cys)-Thr-NH. Similar to the first patent, these compounds also exhibit significant interaction with somatostatin receptors, thus proving invaluable for addressing various medical conditions linked to these receptors. These inventions additionally cover pharmaceutical compositions and their applications in medicament preparation.

Career Highlights

Paternostre has worked extensively with notable companies in the pharmaceutical sector, such as Ipsen Pharma S.a.s and Commissariat à l'Énergie Atomique. His experiences at these organizations have greatly informed his research and invention process, leading to remarkable advancements in the field of peptide therapeutics.

Collaborations

Throughout his career, Paternostre collaborated with distinguished colleagues, including Jean-Christophe Cintrat and Bernard Rousseau. These collaborative efforts have played a crucial role in refining his inventions and advancing therapeutic options available in modern medicine.

Conclusion

Marie-Thérèse Paternostre stands as a notable figure in the realm of innovative medicinal chemistry, with his patents opening new avenues for treatment involving somatostatin. His work not only enhances our understanding of peptide compounds but also paves the way for novel therapeutic strategies. Through his dedication and collaborative spirit, Paternostre continues to contribute immensely to the scientific community and patient care.