Company Filing History:
Years Active: 2000
Title: Marie-Claude Helie: Innovator in Bacterial Mass Production of Taxanes
Introduction
Marie-Claude Helie is a prominent inventor based in Cap-Rouge, Canada. She has made significant contributions to the field of biotechnology, particularly in the production of taxanes and paclitaxel through innovative bacterial methods. Her work has the potential to impact the pharmaceutical industry by providing more efficient ways to produce these important compounds.
Latest Patents
Marie-Claude Helie holds a patent for her invention titled "Bacterial mass production of taxanes and paclitaxel." This patent describes a method for obtaining biologically pure cultures of bacteria isolated from various species of Taxus, including Taxus canadensis, T. brevifolia, T. baccata, T. cuspidata, and T. hunnewelliana. The bacteria, which belong to the genera Sphingomonas, Bacillus, Pantoea, or Curtobacterium, are capable of producing taxanes and paclitaxel in vitro. The invention also includes a process for improving the production of these compounds by culturing bacteria in the presence of a mutagenic agent, leading to the development of new mutated bacteria with enhanced yields of pro-taxane biotransformation.
Career Highlights
Throughout her career, Marie-Claude Helie has focused on the intersection of microbiology and pharmacology. Her innovative approaches have garnered attention in the scientific community, and her work continues to pave the way for advancements in the production of valuable pharmaceutical compounds.
Collaborations
Marie-Claude collaborates with Michel Page, who is also involved in the research and development of biotechnological solutions. Their partnership enhances the potential for breakthroughs in the field.
Conclusion
Marie-Claude Helie's contributions to the field of biotechnology, particularly in the bacterial mass production of taxanes and paclitaxel, highlight her innovative spirit and dedication to advancing pharmaceutical production methods. Her work is a testament to the importance of research and collaboration in driving scientific progress.
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