Marie-Christine Vaney

Title: Marie-Christine Vaney: Innovator in Dengue and Flavivirus Research

Introduction

Marie-Christine Vaney is a prominent inventor based in Paris, France. She has made significant contributions to the field of virology, particularly in the development of vaccines and antibodies against dengue and other flaviviruses. With a total of four patents to her name, her work is crucial in the fight against these infectious diseases.

Latest Patents

Her latest patents include innovative approaches to creating anti-dengue vaccines and antibodies. One notable invention is a Dengue virus Envelope Dimer Epitope (EDE) that spans the polypeptides of a Dengue virus Envelope polypeptide dimer. This EDE can be presented on a dimer of Envelope proteins and is formed from consecutive or nonconsecutive residues of the envelope polypeptide dimer. The dimer can be a homodimer or heterodimer of native and/or mutant envelope polypeptides from any one or two of DENV-1, DENV-2, DENV-3, and DENV-4. Additionally, she has developed a neutralizing antibody against dengue for use in preventing and treating Zika infection, which involves a stabilized recombinant flavivirus EDE.

Career Highlights

Marie-Christine has worked with prestigious institutions such as Institut Pasteur and Imperial College Innovations Limited. Her research has been instrumental in advancing our understanding of flavivirus infections and developing effective vaccines.

Collaborations

Throughout her career, she has collaborated with notable scientists, including Juthathip Mongkolsapaya and Felix Augusto Rey. These partnerships have enhanced her research and contributed to the success of her innovations.

Conclusion

Marie-Christine Vaney's work in the field of virology exemplifies the impact of innovative research on public health. Her patents and collaborations continue to pave the way for advancements in vaccine development against dengue and other flaviviruses.