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Title: The Innovative Contributions of Marianne Mangeney
Introduction
Marianne Mangeney is a prominent inventor based in Paris, France. She has made significant contributions to the field of immunology, particularly in the context of HIV research. With a total of 3 patents to her name, her work has implications for modulating immune responses.
Latest Patents
One of her latest patents involves a mutated HIV Nef protein that is designed to modulate immunity. This patent describes the use of a mutation of at least one amino acid in the immunosuppressive domain of an HIV or SIV accessory protein, aimed at altering the immunosuppressive properties of the protein. Another notable patent focuses on mutated env sequences that are involved in modulating the immunosuppressive effects of viral proteins. These mutated viral ENV proteins, which have changes in the immunosuppressive domain of the transmembrane subunit, exhibit decreased immunosuppressive activity compared to the wild-type ENV protein. Additionally, pharmaceutical compositions that include the protein and nucleic acids coding for the protein are disclosed in this patent.
Career Highlights
Throughout her career, Marianne has worked with esteemed institutions such as the Institut Gustave Roussy and the Centre National de la Recherche Scientifique. Her research has been pivotal in advancing our understanding of viral immunology and developing potential therapeutic strategies.
Collaborations
Marianne has collaborated with notable colleagues, including Martial Renard and Thierry Heidmann. Their joint efforts have contributed to the advancement of research in the field of immunology.
Conclusion
Marianne Mangeney's innovative work in the field of HIV research highlights her significant contributions to immunology. Her patents reflect her commitment to advancing scientific knowledge and developing new therapeutic approaches.