Location History:
- King of Prussia, PA (US) (1998)
- West Chester, PA (US) (1996 - 2000)
Company Filing History:
6 out of 144 
1 out of 560 
1 out of 3 Years Active: 1996-2000
Title: The Innovations of Marian Kruszynski
Introduction
Marian Kruszynski is a notable inventor based in West Chester, PA (US), recognized for his contributions to the field of biomedical research. With a total of seven patents to his name, he has made significant strides in understanding and addressing inflammation and cellular adhesion.
Latest Patents
Kruszynski's latest patents include innovative peptide inhibitors of inflammation mediated by selectins. These peptides, derived from specific regions of the lectin domain of GMP-140 (P-selectin) and related selectins, have demonstrated the ability to inhibit neutrophil adhesion to GMP-140. The synthesized peptides contain core regions from the 74-76 amino acid sequence of GMP-140, with residue 1 defined as the N-terminus of the mature protein. Notably, alterations within the core sequence and flanking regions do not compromise their biological activity. These peptides hold promise for use as diagnostics and, when combined with suitable pharmaceutical carriers, for clinical applications in modulating or inhibiting coagulation and inflammatory processes. Additionally, he has developed peptide inhibitors of cellular adhesion, further showcasing his innovative approach to biomedical challenges.
Career Highlights
Throughout his career, Marian Kruszynski has worked with prominent organizations, including Centocor, Inc. and the University of Oklahoma. His work has significantly impacted the understanding of inflammatory processes and cellular interactions, contributing to advancements in medical science.
Collaborations
Kruszynski has collaborated with notable individuals in his field, including George A. Heavner and Miljenko Mervic. These partnerships have fostered a collaborative environment that enhances research and innovation.
Conclusion
Marian Kruszynski's contributions to the field of biomedical research through his patents and collaborations highlight his role as an influential inventor. His work continues to pave the way for advancements in the understanding and treatment of inflammation and cellular adhesion.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.