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Years Active: 2022
Title: Maria Szaruga: Innovator in Neurodegenerative Disease Research
Introduction
Maria Szaruga is a prominent inventor based in Leuven, Belgium. She has made significant contributions to the field of neurodegenerative diseases, particularly in the development of screening assays that target gamma-secretase enzyme processes. Her work aims to provide solutions for conditions such as Alzheimer’s disease.
Latest Patents
Maria Szaruga holds 1 patent related to her innovative research. The patent, titled "Gamma-secretase stabilizing compound screening assay," focuses on a method to produce compounds that stabilize the gamma-secretase enzyme substrate complex. This invention enhances gamma-secretase processivity while reducing the release of longer Aβ peptides, which are implicated in Alzheimer’s disease. By increasing the thermostability of enzyme/substrate complexes, her work aims to decrease amyloidogenic Aβ production, thereby offering potential therapeutic avenues for preventing Alzheimer’s disease.
Career Highlights
Throughout her career, Maria has worked with notable organizations such as Vib Vzw and Katholieke Universiteit Leuven, also known as KU Leuven R&D. Her research has been pivotal in advancing our understanding of neurodegenerative diseases and developing innovative solutions.
Collaborations
Maria has collaborated with esteemed colleagues, including Bart De Strooper and Lucia Chávez Gutiérrez. These partnerships have enriched her research and contributed to the advancement of knowledge in her field.
Conclusion
Maria Szaruga is a dedicated inventor whose work in neurodegenerative disease research is making a significant impact. Her innovative approaches and collaborations are paving the way for future advancements in the treatment of Alzheimer’s disease.