Munich, Germany

Maria-Regina Kula

USPTO Granted Patents = 40 


Average Co-Inventor Count = 3.4

ph-index = 10

Forward Citations = 357(Granted Patents)


Location History:

  • Niederziehr-Hambach, DE (1989)
  • Niederzier/Hambach, DE (1989 - 1993)
  • Niederziehr/Hambach, DE (1993)
  • Niederzier-Hambach, DE (1989 - 1994)
  • Wolfenbuttel, DE (1979 - 1995)
  • Hambach-Niederzier, DE (1999 - 2001)
  • Niederzier, DE (1992 - 2008)
  • München, DE (2007 - 2011)

Company Filing History:


Years Active: 1979-2011

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Areas of Expertise:
Plasmid-DNA Extraction
Nitrile Hydratase
Protein Partitioning
Peptide Amidase
Enzyme Purification
Optically-Active Compounds
Microbiological Production
Aqueous Biphasic Systems
Racemization Processes
Formate Dehydrogenase
Enzymatic Conversion
Ion-Exchange Chromatography
40 patents (USPTO):Explore Patents

Title: Maria-Regina Kula: Innovator in Biotechnology

Introduction: Maria-Regina Kula, based in Munich, Germany, is a prominent inventor in the field of biotechnology, known for her substantial contributions to scientific research and innovations. With an impressive portfolio of 40 patents, Kula has made significant strides in methods for DNA isolation and enzyme activation.

Latest Patents: Among her latest inventions, Kula developed a method for obtaining plasmid-DNA using an aqueous biphasic system. This innovative process improves the isolation of plasmid DNA from biomass by utilizing a one-pot procedure where alkaline lysis and neutralization occur in a single reaction vessel, optimizing efficiency. Another notable patent involves a polynucleotide cluster that encodes sequences for nitrile hydratase, an auxiliary protein, and a cobalt transporter. This invention showcases transformed microorganisms capable of efficiently preparing amides from nitriles, marking an advancement in biocatalysis.

Career Highlights: Maria-Regina Kula's professional journey includes significant experiences with distinguished organizations. She has worked with Degussa Aktiengesellschaft, a leader in the chemical industry, and Forschungszentrum Juelich GmbH, renowned for its research in complex scientific challenges. Her tenure at these institutions has been marked by notable advancements in biotechnological applications.

Collaborations: Throughout her career, Kula has collaborated with esteemed colleagues such as Wolfgang Leuchtenberger and Werner Hummel. These partnerships have enriched her research, leading to groundbreaking innovations and enhancing the impact of her work in the scientific community.

Conclusion: Maria-Regina Kula stands out as a formidable figure in biotechnology, with her inventions significantly pushing the boundaries of scientific knowledge and application. Her dedication to innovation, as evidenced by her numerous patents and collaborative efforts, continues to inspire advancements in the field.

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