Maria Altamura

Title: Maria Altamura: Innovator in Penem Preparation

Introduction

Maria Altamura is a distinguished inventor based in Novara, Italy. She has made significant contributions to the field of chemistry, particularly in the preparation of penems. With a total of four patents to her name, Altamura's work has advanced the understanding and application of these important compounds.

Latest Patents

Among her latest patents is a process for the preparation of penems, which involves an in vitro method for creating 6((1R)-hydroxyethyl) penem acids. This process utilizes an enzyme capable of selectively hydrolyzing the ester group at the 3-position of the carboxylic acid ester. The enzymatic hydrolysis is conducted at a pH range of 5 to 8 and at temperatures between 20°C and 40°C. Another notable patent describes a process for preparing a compound of a specific formula, where R1 represents a hydroxy protecting group and R2 represents a carboxy protecting group.

Career Highlights

Throughout her career, Maria Altamura has worked with prominent companies in the pharmaceutical industry, including Farmitalia Carlo Erba S.p.a. and Farmitalia Carlo Erba S.r.l. Her expertise in the field has allowed her to develop innovative processes that enhance the production of vital pharmaceutical compounds.

Collaborations

Maria has collaborated with notable colleagues such as Franco Francalanci and Marcello Marchi. These partnerships have contributed to her success and the advancement of her research.

Conclusion

Maria Altamura is a remarkable inventor whose work in penem preparation has made a significant impact in the field of chemistry. Her patents and collaborations reflect her dedication to innovation and excellence in her field.