Company Filing History:
Years Active: 2004-2011
Title: Margret Becker: Innovator in Factor VII-Activating Protease Research
Introduction
Margret Becker is a distinguished inventor based in Marburg, Germany. She has made significant contributions to the field of biomedical research, particularly in the area of blood coagulation and diagnostic methods. With a total of 5 patents, her work has advanced the understanding of factor VII-activating protease and its implications in arterial thrombosis.
Latest Patents
Among her latest patents, Becker has developed mutants of the factor VII-activating protease and detection methods using specific antibodies. These mutants include alterations in the DNA sequence coding for the protease, which activates blood clotting factor VII. The specific mutations involve a G/C base exchange at nucleotide position 1177 and/or a G/A base exchange at nucleotide position 1601. The corresponding protease exhibits a Glu/Gln exchange at amino acid position 393 and/or a Gly/Glu exchange at amino acid position 534. Furthermore, she has described diagnostic methods for detecting FSAP in body fluids or tissue cells, which can identify patients with genetic heterozygous or homozygous FSAP expression. Another notable patent addresses the Marburg I mutant of factor VII-activating protease as a risk factor for arterial thrombosis, along with methods for detecting these mutants.
Career Highlights
Throughout her career, Margret Becker has worked with prominent companies such as CSL Behring GmbH and Aventis Behring GmbH. Her research has not only contributed to scientific knowledge but has also had practical applications in the medical field.
Collaborations
Becker has collaborated with notable colleagues, including Juergen Roemisch and Thomas Weimer. These partnerships have further enriched her research and expanded the impact of her innovations.
Conclusion
Margret Becker's work in the field of factor VII-activating protease research exemplifies her dedication to advancing medical science. Her patents and collaborations highlight her significant contributions to understanding blood coagulation and its associated risks.