Company Filing History:
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Years Active: 2012-2025
Title: Margarita Salas Falgueras: A Pioneer in DNA Polymerase Research
Introduction
Margarita Salas Falgueras is a renowned inventor and scientist based in Madrid, Spain. She has made significant contributions to the field of molecular biology, particularly in the development of DNA polymerases. Her innovative work has led to the filing of several patents, showcasing her expertise and dedication to advancing scientific knowledge.
Latest Patents
Margarita Salas Falgueras holds 3 patents that reflect her groundbreaking research. One of her latest inventions is titled "Primer-independent DNA polymerases and their use for DNA synthesis." This invention provides an isolated peptide necessary for primase activity, along with new replicative DNA polymerase enzymes. These polymerases are capable of initiating and performing DNA amplification without the need for externally provided primers. They can conduct faithful and processive de novo DNA synthesis of DNA templates, even in the absence of pre-synthesized primers. Additionally, these enzymes exhibit translesion synthesis capacity, making them useful for amplifying damaged DNAs.
Another notable patent is the "Phage phi29 DNA polymerase chimera." This invention describes a DNA polymerase chimera that includes an amino-terminal region encoding a φ29 type DNA polymerase and a carboxyl-terminal region comprising at least one HhH domain. This chimera is designed for replicating, amplifying, or sequencing template DNA, and it comes with methods and kits for carrying out these processes.
Career Highlights
Throughout her career, Margarita has worked with prestigious institutions, including the Consejo Superior de Investigaciones Científicas and Institut Pasteur. Her work has not only advanced the field of molecular biology but has also paved the way for new methodologies in DNA research.
Collaborations
Margarita has collaborated with notable colleagues, including Miguel De Vega Jose and Jose M Lazaro Bolos. These collaborations have further enriched her research and contributed to her success as an inventor.
Conclusion
Margarita Salas Falgueras is a distinguished inventor whose contributions to DNA polymerase research have had a lasting impact on molecular biology. Her innovative patents and collaborations highlight her role as a leader in scientific advancement.