Company Filing History:
Years Active: 2001
Title: The Innovative Contributions of Margaret A. Hirst
Introduction
Margaret A. Hirst is a notable inventor based in Redwood City, CA. She has made significant contributions to the field of biotechnology, particularly in the development of assays for anti-stress agents. Her work has implications for understanding cellular responses to stress and potential therapeutic interventions.
Latest Patents
Margaret A. Hirst holds a patent for an "Assay system for anti-stress agents." This invention provides methods and compositions for screening compounds that exhibit anti-stress activity. The patent utilizes a rat hepatoma-derived cell line that is particularly responsive to agents that inhibit mitochondrial function. The assay demonstrates the extracellular release of lactate dehydrogenase and the formation of lactate, which are critical indicators of cellular stress. Furthermore, cytoprotectant agents are shown to reverse lactate dehydrogenase release in the presence of mitochondrial function interfering agents, serving as a model for the effects of hypoxia on cellular energetic function.
Career Highlights
Margaret A. Hirst has dedicated her career to advancing the understanding of cellular mechanisms related to stress and mitochondrial function. Her innovative approach has led to the development of valuable tools for researchers in the field. She is currently associated with Galileo Laboratories, Inc., where she continues to explore the intersection of biotechnology and health.
Collaborations
Margaret has collaborated with various professionals in her field, including her coworker Guy Miller. Their combined expertise has contributed to the advancement of research in anti-stress agents and cellular health.
Conclusion
Margaret A. Hirst's contributions to the field of biotechnology through her innovative patent and collaborative efforts highlight her role as a significant inventor. Her work continues to pave the way for future research and applications in understanding and mitigating stress at the cellular level.