Margalit B Mokyr

Title: Margalit B Mokyr: Innovator in Tumor Cell Preservation

Introduction

Margalit B Mokyr is a notable inventor based in Skokie, IL (US). She has made significant contributions to the field of medical technology, particularly in the preservation of tumor cells for immunotherapy.

Latest Patents

Mokyr holds a patent for the "Cryopreservation of haptenized tumor cells." This innovative method involves using a freezing medium that contains an effective amount of sucrose and human serum albumin in an isotonic buffered saline solution. The process has been shown to maintain the integrity of tumor cells during storage. The haptenized tumor cells retain cell-associated antigens and haptens, making them as immunogenic as fresh vaccines in a mouse model of metastatic disease. Specifically, the method involves exposing haptenized cells to a solution of 8% sucrose and 10% human serum albumin in Hank's buffered solution, followed by freezing at -80°C overnight and storing in a liquid nitrogen freezer.

Career Highlights

Throughout her career, Mokyr has focused on advancing techniques in cryopreservation and immunotherapy. Her work has the potential to enhance the effectiveness of cancer treatments by improving the storage and viability of tumor cells used in vaccines.

Collaborations

Mokyr has collaborated with esteemed colleagues such as Lorne F Erdile and David Berd. These partnerships have contributed to her innovative research and development in the field.

Conclusion

Margalit B Mokyr's contributions to the preservation of haptenized tumor cells represent a significant advancement in cancer immunotherapy. Her innovative methods have the potential to improve treatment outcomes for patients.