Manchester, United Kingdom

Marco Fiorillo

USPTO Granted Patents = 2 

 

Average Co-Inventor Count = 3.0

ph-index = 1


Company Filing History:


Years Active: 2022-2025

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2 patents (USPTO):Explore Patents

Title: The Innovative Contributions of Marco Fiorillo in Cancer Research

Introduction

Marco Fiorillo, an accomplished inventor based in Manchester, GB, has made significant strides in the field of cancer research. With a strong focus on understanding and combating endocrine therapy resistance in cancer cells, he has been credited with two impactful patents that highlight his expertise and dedication to improving treatment outcomes for patients. Currently, Marco is affiliated with Lunella Biotech, Inc., where he collaborates with fellow researchers to advance therapeutic innovations.

Latest Patents

Marco Fiorillo's latest patents reflect his commitment to pioneering advancements in oncology. His first patent focuses on "Biomarkers and therapeutics for endocrine therapy resistance." This innovative work highlights how cancer cells can acquire resistance to treatments like Tamoxifen through mutations such as Y537S. By identifying specific biomarkers that exhibit prognostic value, Marco has outlined therapeutic strategies to counteract mitochondrial biogenesis, providing new avenues for improving endocrine therapy effectiveness.

His second patent, titled "Energetic cancer stem cells (e-CSCs): a new hyper-metabolic and proliferative tumor cell phenotype driven by mitochondrial energy," describes a distinct subgroup of cancer stem cells with a unique energetic profile. These e-CSCs demonstrate increased glycolytic activity and mitochondrial mass, making them more susceptible to targeted mitochondrial therapies. Through his research, Marco has established new insights into targeting the energetic properties of e-CSCs, potentially revolutionizing cancer treatment approaches.

Career Highlights

Marco Fiorillo has established himself as a prominent figure in cancer research, with a keen focus on elucidating the mechanisms behind therapy resistance. His innovative patents contribute to the scientific community's understanding of how cancer cells adapt and overcome treatment challenges. As he continues to explore these essential areas of study, Marco's work stands at the forefront of efforts to enhance cancer therapeutics and patient outcomes.

Collaborations

Collaboration has played a vital role in Marco's research journey. He works alongside accomplished colleagues, including Michael P. Lisanti and Federica Sotgia. Together, they form a dynamic team at Lunella Biotech, Inc., where they share a common goal of pushing the boundaries of cancer research. Their combined expertise and innovative thinking foster an environment ripe for breakthroughs in understanding cancer biology and developing new therapeutic strategies.

Conclusion

Marco Fiorillo's dedication to innovation and research in cancer therapeutics underscores his importance in the field. With groundbreaking patents addressing the challenges of endocrine therapy resistance and targeting energetic cancer stem cells, he continues to contribute to the ongoing battle against cancer. Through collaboration with talented researchers and a relentless pursuit of knowledge, Marco Fiorillo is poised to make a lasting impact on cancer treatment, offering hope for improved patient outcomes.

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