This inventor holds 4 USPTO granted patents and 1 published patent application and 1 EPO patent. Top assignee: Erregierre S.p.a.. Active years: 2005-2013.
Location History:
- Curno, IT (2005 - 2008)
- Cumo, IT (2013)
Company Filing History:
Years Active: 2005-2013
Title: Marcello Ghezzi: Innovator in Pharmaceutical Chemistry
Introduction
Marcello Ghezzi is a notable inventor based in Curno, Italy. He has made significant contributions to the field of pharmaceutical chemistry, holding a total of 4 patents. His work focuses on innovative processes for synthesizing important pharmaceutical compounds.
Latest Patents
One of Marcello Ghezzi's latest patents is a process for the synthesis of cinacalcet hydrochloride. This process involves several steps, including the reaction of (R)-(+)-1-(1-naphthyl)ethylamine with 3-[3-(trifluoromethyl)phenyl]propenaldehyde to create a non-isolated intermediate. The subsequent steps include reducing this intermediate and hydrogenating it to obtain cinacalcet base, which is then treated with hydrochloric acid to yield cinacalcet hydrochloride. Another significant patent is for the preparation of 1-(aminomethyl) cyclohexaneacetic acid. This process converts gabapentin hydrochloride into gabapentin through a dissolution and precipitation method, allowing for the removal of the chloride ion.
Career Highlights
Marcello Ghezzi is currently employed at Erregierre S.p.a., where he continues to develop innovative pharmaceutical processes. His expertise in chemical synthesis has positioned him as a valuable asset in the industry.
Collaborations
Throughout his career, Marcello has collaborated with notable colleagues, including Massimo Ferrari and Paolo Belotti. These partnerships have contributed to the advancement of his research and the successful development of his patents.
Conclusion
Marcello Ghezzi's contributions to pharmaceutical chemistry through his innovative patents demonstrate his commitment to advancing medical science. His work continues to impact the field positively, showcasing the importance of innovation in healthcare.