Company Filing History:
Years Active: 1996-2006
Title: The Innovations of Marc Spingola
Introduction
Marc Spingola is a notable inventor based in Albuquerque, NM (US). He has made significant contributions to the field of nucleic acid amplification, holding a total of 6 patents. His work focuses on developing methods that enhance the efficiency and effectiveness of amplifying target nucleic acid sequences.
Latest Patents
One of Marc Spingola's latest patents is centered on isothermal strand displacement nucleic acid amplification. This method utilizes a nucleic acid polymerase that lacks 5' exonuclease activity, along with a set of oligonucleotide primers. The innovation involves the use of a primer array that contains two sets of primers. One set includes at least two complementary primers, while the other set consists of at least two sense primers. This approach allows for amplification to be conducted under essentially constant environmental conditions, eliminating the need for exonuclease activity or restriction endonuclease activity.
Career Highlights
Marc Spingola is currently associated with Gen-Probe, Inc., where he continues to advance his research and development efforts. His work has been instrumental in improving nucleic acid amplification techniques, which have broad applications in various fields, including diagnostics and research.
Collaborations
Throughout his career, Marc has collaborated with esteemed colleagues such as Paul Douglas Stull and Nanibhushan Dattagupta. These partnerships have contributed to the success and impact of his innovations.
Conclusion
Marc Spingola's contributions to nucleic acid amplification represent a significant advancement in the field. His innovative methods and collaborative efforts continue to influence research and development in biotechnology.