This inventor holds 34 USPTO granted patents and 10 published patent applications, plus 6 CIPO patents and 5 EPO patents, primarily in Molecular Flux Measurement. Top assignees: University of California, Kinemed, Inc., Glaxosmithkline LLC. Active years: 1994-2019.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
32 out of 16,035 
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Years Active: 1994-2019
Areas of Expertise:
Title: The Innovative Contributions of Marc K. Hellerstein
Introduction
Marc K. Hellerstein, based in Kensington, California, is a prolific inventor with a remarkable portfolio of 34 patents. His pioneering work spans several significant advancements in the biomedical field, particularly related to metabolic processes and drug action. Hellerstein's research has made substantial contributions to understanding the therapeutic efficacy and potential toxic effects of various compounds.
Latest Patents
Hellerstein's latest inventions focus on measuring molecular flux rates through critical pathways using stable isotope labeling in vivo. These methods enable researchers to evaluate compounds administered to subjects to assess their therapeutic efficacy or toxic effects. By targeting underlying biochemical processes involved in disease pathogenesis, he has created a powerful approach to understanding drug mechanisms. The patents allow for molecular flux rates to be compared between test subjects and control subjects, providing crucial information on a drug's effectiveness or toxicity. Moreover, his methodologies facilitate the evaluation of combinations of compounds for their complementary, synergistic, or antagonistic effects on metabolic pathways, paving the way for novel therapeutic applications.
Another notable patent from Hellerstein includes methods for spatially measuring molecular flux rates in tissue samples. This innovation allows for the generation of comprehensive outputs such as images, heat maps, and databases, providing a detailed view of molecular activity within defined spatial locations. His work significantly enhances the ability to analyze molecular processes within tissues, offering essential insights for both therapeutic and research applications.
Career Highlights
Hellerstein's distinguished career includes significant positions at reputable institutions such as the University of California and Kinemed, Inc. His expertise and research have not only added to the scientific community's understanding of metabolites and drugs but have also positioned him as a leader in his field. His notable contributions have garnered respect among fellow researchers and have influenced ongoing studies in drug development and metabolic research.
Collaborations
Throughout his career, Marc K. Hellerstein has collaborated with distinguished colleagues, including Martin Decaris and Mahalakshmi Shankaran. These collaborations have fostered an environment of innovation and have facilitated the advancement of his research endeavors. Working alongside talented individuals has led to the fruitful exchange of ideas and the development of new methodologies that continue to push the boundaries of biomedical research.
Conclusion
In summary, Marc K. Hellerstein's innovative pursuits and deep understanding of metabolic processes have established him as a leading inventor in the field of biomedical research. His extensive patent portfolio reflects his commitment to advancing science and improving therapeutic strategies. Through his inventive work, Hellerstein continues to impact the landscape of drug research, ultimately contributing to better health outcomes.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile