El Sobrante, CA, United States of America

Marc D Whitlow


Average Co-Inventor Count = 3.7

ph-index = 15

Forward Citations = 680(Granted Patents)


Location History:

  • El Sabrante, CA (US) (1998)
  • Princeton, NJ (US) (1999)
  • Gaithersburg, MD (US) (1999 - 2000)
  • El Sobrante, CA (US) (2000 - 2009)

Company Filing History:


Years Active: 1998-2009

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20 patents (USPTO):Explore Patents

Title: **The Innovative Journey of Marc D. Whitlow**

Introduction

Marc D. Whitlow, based in El Sobrante, California, is an accomplished inventor with an impressive portfolio of 20 patents. His work significantly contributes to the field of biotechnology, particularly in the development of therapeutic applications involving polypeptides.

Latest Patents

Among his most recent inventions is the patent for Polyalkylene oxide-modified single chain polypeptides. This innovation addresses the chemical modification of single chain polypeptides through the covalent attachment of poly(ethylene glycol) (PEG) and similar poly(alkylene oxides). These modified polypeptides exhibit three-dimensional folding, retaining the binding ability and specificity akin to the variable region of an antibody. This advancement has resulted in preparations that have reduced immunogenicity and antigenicity, offering a longer half-life in the bloodstream compared to their parent polypeptides. Such properties make these innovations crucial for various therapeutic applications, including the development of multivalent antigen-binding molecules capable of PEGylation. Whitlow’s detailed disclosures in his patent cover compositions, genetic constructions, methods of use, and processes for producing PEGylated antigen-binding proteins.

Career Highlights

Throughout his career, Marc has made significant strides in biotechnology. He has worked with reputable organizations, including Enzon, Inc. and Enzon Pharmaceuticals, Inc. His expertise has not only enhanced his professional journey but has also pushed the boundaries of innovation in therapeutic development.

Collaborations

In his endeavors, Marc collaborated with notable professionals such as David R. Filpula and Karl D. Hardman. These partnerships have fostered a productive exchange of ideas and expertise, further propelling advancements in the field of biotechnology.

Conclusion

Marc D. Whitlow's contributions to the field through his patents reflect his commitment to innovation and improving therapeutic techniques. His work serves as a testament to the crucial role inventors play in shaping the future of medicine through inventive solutions and collaborative efforts.

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