Maoliang Wang

Title: The Innovations of Maoliang Wang

Introduction

Maoliang Wang is a prominent inventor based in East Brunswick, NJ (US), known for his significant contributions to the field of biotechnology. With a total of 10 patents to his name, Wang has made remarkable advancements in gene delivery systems and enzyme production.

Latest Patents

One of Wang's latest patents is titled "Recombinant host for producing L-asparaginase II." This invention provides a recombinant host cell designed for the production of the L-asparaginase II enzyme. The host cell includes a chromosome and at least one copy of a recombinant extrachromosomal vector, which encodes the L-asparaginase II enzyme. Importantly, the host cell chromosome also encodes the same enzyme, while not encoding any other isoform of L-asparaginase II. Another notable patent is the "Method for targeted delivery of nucleic acids." This invention focuses on a method for in vivo and ex vivo gene delivery applicable to various cell types. It introduces a novel carrier system comprising single-chain polypeptide binding molecules that have a region rich in basic amino acids, enhancing their ability to bind nucleic acids. These innovations are particularly valuable in therapeutic applications, including gene therapy.

Career Highlights

Throughout his career, Maoliang Wang has worked with several notable companies, including Enzon, Inc. and Defiante Farmaceutica, S.A. His work in these organizations has contributed to the development of cutting-edge biotechnological solutions.

Collaborations

Wang has collaborated with esteemed colleagues such as David R. Filpula and Marc D. Whitlow, further enhancing the impact of his research and innovations.

Conclusion

Maoliang Wang's contributions to biotechnology through his patents and collaborations highlight his role as a leading inventor in the field. His work continues to influence advancements in gene therapy and enzyme production, showcasing the importance of innovation in science.